Overdose of Antiparasitic

Teddscau

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Budgies: Sunshine, Blanco, Azure; Peach-faced lovebirds: Rosie and Jaybird; YSA: Jasper (ā™€)
Okay, so I'm freaking out. Gave the birds their doses of Revolution, but we accidentally gave Lara, Ria, and Ziggy twice as much as they should've. Lara was supposed to have 5 doses, but we gave her 8ā€”10ish. Because we were using this pipette, but, we sucked up too much liquid each dose for these three birds. We were only supposed to depress the thingy half way, but we did it the full way.

This happened, an hour ago? It took a while to medicate everyone. We wiped off some of the medicine with a microfibre cloth off the three, but I don't know if we got enough off. Selamectin has a bigger safety barrier thing than Ivermectin (ivermectin is easily overdosed, but Selamectin/Revolution is safer).

Fudge, so Revolution is considered really safe, but, if they get too much, it crosses the blood/brain barrier, and they can pee blood, become disoriented, have convulsions, go into a coma, or even die. But, like, apparently this doesn't really happen all that often, even with overdoses?

You guys have a clear mind, here!

https://www.drugs.com/pro/revolution-topical.html
http://parasitipedia.net/index.php?option=com_content&view=article&id=2671&Itemid=2948
https://wagwalking.com/condition/selamectin-toxicity-

Like, Lara was supposed to have 25 micrograms, but she got something like 50 micrograms. Ria was supposed to have 20 micrograms, but she had 40 or so micrograms. Ditto for Ziggy.
 
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Tami2

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Aug 18, 2017
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Levi - 6 yr old CAG

DOH-4/2/2016
Iā€™m so sorry, Iā€™d be freaking out to. I know nothing about this. Clearly, itā€™s to late to call your Vet. I hope theyā€™ll be okay.
 
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Teddscau

Teddscau

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Sep 25, 2015
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Budgies: Sunshine, Blanco, Azure; Peach-faced lovebirds: Rosie and Jaybird; YSA: Jasper (ā™€)
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Gah, the only thing going in our favour is that it's applied topically, rather than ingested. On another note, wild budgies regularly bathe in and ingest eucalyptus, and kākāriki consume and smear kanuka and manuka on themselves. However, those are toxic plants, not toxic parasite medicine.

Anyways, thanks for your thoughts. Hopefully they'll be okay. Now I'm glad they were prescribed Revolution rather than Ivermectin (they would probably be coughing up blood right now if it was Ivermectin). I'll be playing video games in the basement until 2 am, so I'll check on them every 15ā€“30 minutes for side-effects (I'm like 15' away from the aviary). Fudge, we must sound terrible (Mom was helping). Fudge, well, a lot of Lara's weight is fat and muscle, so hopefully those useless cells soak up the excess medicine.

Fudge, need to think positively. Umm, Samantha was wearing a vine ring around her neck last night like a necklace when I checked on them. It was from one of their vine balls, and I guess she stuck her head through it and couldn't get it off. We took it off her and she was fine.
 
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Kentuckienne

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Oct 9, 2016
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Iā€™d call the vet when they open, but you might be OK.

The first web page linked says Revolution was applied to puppies and kittens at 1, 3, 5, and 10 times the normal dose and no adverse reactions were observed. Some animals are sensitive to the chemicals and are affected even at the regular dose. If you were able to wipe most of the product off the birds that should help. The literature says that after two hours, the animal can be bathed. Does that mean itā€™s all been absorbed in two hours, or does it mean that the alcohol carrier has evaporated and the drug isnā€™t soluble? I would guess the former, because they donā€™t say anything about soap or other products that might wash dried product off. So if it takes two hours to fully absorb, and you caught it right away, you might be ok. Hereā€™s an article discussing the off-label use of the drug in exotic pets, saying that the maximum blood concentration is higher in cats than in dogs - it seems to cross the skin more easily - and that the rate of absorption in rats is faster than in cats but slower than in dogs. You wiped it off right away...

http://www.jarvm.com/articles/Vol5Iss3/Beck 87-96.pdf
 
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Teddscau

Teddscau

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Sep 25, 2015
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Ontario, Canada
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Budgies: Sunshine, Blanco, Azure; Peach-faced lovebirds: Rosie and Jaybird; YSA: Jasper (ā™€)
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Good news, everyone's fine ;).
 

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