With great luck, all of our Amazons, over the years, have been road warriors and loved to travel. Our Julio's prior owners traveled from Northern Michigan to the Southern coast of Texas yearly and we have for years traveled from Western Michigan to the Tampa area of Florida.
I'll not into a full-out push to make the trip in one full run... It's hard on everyone and everyone will be dead tired when you arrive, which is not good for anyone other than 20 somethings traveling for Spring Break. Our Amazons have all been elderly and handled the trip well. We have always played it by ear. Harsh Weather slows things down, Road Construction and hitting rush hour traffic, and traffic back-ups are common unknowns that can take a perfectly time trip and turn it into a nightmare if your goal is to push though.
Traffic lights and traveling with an elderly Amazon: The red tail lights have always been an issue with our Amazons as have the on-coming head lights. So, I would recommend not traveling deep into the night. Yes, you can cage cover, but that can be problematic as well.
Center the travel cage in the back seat so that both of you are visible is a better choice as it keeps the drafts common along the doors to a minimum and temperature tends to be more balanced. GPS has taken much of the need for the non-driver to keep track of things, but a map is always helpful for the big picture.
Assure you have a complete copy of your Amazon's Medical file with you. Also, find and map-out the location of Avian Medical Professional's clinics and phone numbers along the way. We have been very lucky and have never had to use it, but...
Your Amazon is already a proven traveler and what you have experienced will be what you will see on the longer trip. Long story short, plan for a single night stop but be open to a couple of nights if needed.