I ask for help in the treatment of African parrot

[Aquila]

The litter looks like wood pellets or something like Kay-Kob. I only use newspaper or paper towels in my cages. Pellet litter can hold on to too much moisture and grow mold. Kay-Kob is made from corn cobs.

Using something like paper towels right now might be good because they're white and you can look at her dropping better so you can see if anything changes.

 

[Kentuckienne]

There is a lot of research about aspergillosis and other fungus organisms in corn granules bedding (litter).

Here is one that is easier to understand, written by a bird owner.
https://www.beautyofbirds.com/aspergillosisparrots.html

Here is a US government health agency study, it is technical, the summary is they tested corncob bedding of two rats who had died of respiratory disease and found lots of asper and other fungi in many of the samples they tested.

https://www.ncbi.nlm.nih.gov/pubmed/12086454

Another scientific veterinary article:
https://www.forthebirdsdvm.com/pages/aspergillus-sinusitis-in-a-cockatiel

 

[Lidia]

Thank you, thank you !!! How much information I learned from your links, I regret why I did not come to your site before.

 

[Lidia]

I buy a medicine for 200 mg (Voriconazole), it costs 20,000 rubles (or 357 dollars) made an order, it should come to our city in two days, it will be enough for a certain time.
And I also found https://www.ebay.co.uk/itm/Asperzole-for-Birds-50-tablets/182916553058
but I can not understand the exact composition? Will it fit my bird.?
And the main thing is that this drug does not always come to Russia from this site, so I'm thinking about how to order it.

 

[Aquila]

Wow that's expensive! I don't recommend buying from ebay, but I understand your situation.

This is the product.
Asperzole Tablets - Vetafarm

It says it's 12.5mg of Voriconazole per tablet. Please ask your vet for proper dosage, but you may be able to crush into a powder and mix with soft food.

 

[Scott]

Can you purchase from a Canadian pharmacy? https://www.canadadrugpharmacy.com/search.asp

Perhaps European nations will produce and mail order for you?

In any case, very important to deliver the proper dosage. Your veterinarian or the pharmacy tech should be able to demonstrate the proper method.

 

[Lidia]

Hello! And why do not you recommend buying on ebay?
this is the only place where I found a more suitable dosage, we only have 200 mg tablets in a human pharmacy

 

[Lidia]

it is interesting to learn from practice how to treat voriconazole in your US, because here no one writes about it, and veterinarians give about 18 g per 1 kg

 

[Aquila]

Hello! And why do not you recommend buying on ebay?
this is the only place where I found a more suitable dosage, we only have 200 mg tablets in a human pharmacy

It's sometimes hard to tell if the seller is reputable. You have to be careful of counterfeit or contaminated products. They might also be expired.

 

[Aquila]

I'm sorry if these articles are difficult to understand, but they have some other information about medications used to treat aspergillosis.

Fungal diseases of pet birds: Recognize infection early

Aspergillosis

Acute and Chronic Aspergillosis in Birds: Causes, Signs, Treatment, and Prevention

 

[Lidia]

Yes, I found out that the Canadian pharmacy is not supplied to Russia , but I can order it from Europe, but I need to pay about 572 euros. it is very expensive, like two wages

 

[Lidia]

Today they told me that they found it in Moscow: Vfend (Pfizer) in a suspension of 40 mg (voriconazole), it can be more accurately divided, but this packing is sealed, for use it is necessary to divide 45 grams (this into dry matter in a bottle) 5 grams, and is thus stored in a dissolved form for 14 days.
But the question arose whether it is possible to store the remainder ungermatically, I called the representative office of Pfizer in Russia, but they do not know, and throw the phone down.
Here I want to know whether you can ask a question to official representatives, I will be very grateful to you!
Address: 280 Shennecossett Rd, Groton, CT 06340, USA
Phone: +1 860-441-4100
(Pharmaceutical company in Groton, Connecticut)
or
Pfizer Inc.
235 East 42nd Street NY, NY 10017
(212) 733-2323
I wrote to them, but it's long, I want to start treating my gray African parrot soon!
Thanks in advance!


p.s. The question is: can the powder of the suspension be fraction (divide) and partially dissolved and the residues stored in the refrigerator.
Does not lose its properties "voriconazole" when it comes in contact with oxygen while storing an already open bottle ?!
So I wrote them in instagrams: Tell me please, can you divide the powder Vfend (Pfizer) in a suspension of 40 mg (voriconazole), divide 45 grams of powder,dissolve, а the rest and keep the rest in the refrigerator and dissolve in a month.

 

[Aquila]

This has some information here.
https://www.pfizermedicalinformation.com/en-us/vfend/storage-handling

The powder seems to be good for 24 months when unmixed and stored in the refrigerator.

The mixed powder you want at room temperature, and it's good for 14 days.

You can probably call a local pharmacy and verify proper storage, but the dry powder is sterile, so you just have to avoid contamination.

I also found an email for the Russian Pfizer office, [email protected] and their website is https://www.pfizermedinfo.ru/ru-ru

 

[Lidia]

Thank you very much for answering.
Yes, I called to our representative office, but they could not reply

 

[Lidia]

as I understood from their site that it's okay if i split the powder

 

[Scott]

Suggested dosing information for Greys: https://www.ncbi.nlm.nih.gov/pubmed/18167096

Article describing anti-fungal medicines begins on page 9 (numbers at bottom of pages) http://www.exoticpetmedicine.com/article/S1557-5063(13)00216-4/pdf

Storey Marketing

 

[Kentuckienne]

We have done this, and yes the powder will be fine to keep. One rule is never put anything in the bottle. Carefully tap out the amount you need onto a paper on a scale, or use a clean, dry spoon to take it out of the bottle. Never put powder back in the bottle - if you take too much, put that into a second clean dry bottle to use next time. This keeps the main bottle clean.

When we did this for a sick bird, the vet said to keep the dissolved powder in the refrigerator to prevent any organisms from growing in it.

 

[Lidia]

Thank you! Today we will start giving him medicine.

 

[Scott]

Great job, hopefully Jaquo will respond well to the medicine. I would recommend preparing the solution the same way each time so it becomes familiar, with less chance of error. Let us know if you have difficulty giving him the medicine, there are different techniques to ensure it is fully consumed.

 

[Lidia]

Hello! it is interesting to read what methods exist for parrots, since he must swallow all the medicine, of course, do not want to force, but if my parrot does not drink, then I have to force him to drink.